amoxicillin and subactam injection is an antibiotic used to treat a number of bacterial infections These include middle ear infection, strep throat, pneumonia, skin infections, and urinary tract infections among others It is taken by mouth, or less commonly by injection
Common adverse effects include nausea and rash It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea It should not be used in those who are allergic to penicillin While usable in those with kidney problems, the dose may need to be decreased] Its use in pregnancy and breastfeeding does not appear to be harmful Amoxicillin is in the beta-lactam family of antibiotics
Amoxicillin was discovered in 1958 and came into medical use in 1972 It is on the World Health Organization’s List of Essential Medicines It is one of the most commonly prescribed antibiotics in children Amoxicillin is available as a generic medication In 2018, it was the seventeenth most commonly prescribed medication in the United States, with more than 31 million prescriptions
amoxicillin and subactam injection is used in the treatment of a number of infections, including acute otitis media, streptococcal pharyngitis, pneumonia, skin infections, urinary tract infections, Salmonella infections, Lyme disease, and chlamydia infections
Acute otitis media
Children with acute otitis media who are younger than 6 months of age are generally treated with amoxicillin or other antibiotics. Although most children with acute otitis media who are older than two years old do not benefit from treatment with amoxicillin or other antibiotics, such treatment may be helpful in children younger than two years old with acute otitis media that is bilateral or accompanied by ear drainage In the past, amoxicillin was dosed three times daily when used to treat acute otitis media, which resulted in missed doses in routine ambulatory practice. There is now evidence that two times daily dosing or once daily dosing has similar effectiveness
Respiratory infections
have been recommended by guidelines as the drug of choice for bacterial sinusitis and other respiratory infectionsMost sinusitis infections are caused by viruses, for which amoxicillin and amoxicillin-clavulanate are ineffective,and the small benefit gained by amoxicillin may be overridden by the adverse effects amoxicillin injection recommended as the preferred first-line treatment for community-acquired pneumonia in adults by the National Institute for Health and Care Excellence, either alone (mild to moderate severity disease) or in combination with a macrolide The World Health Organization recommends amoxicillin as first-line treatment for pneumonia that is not is used in post-exposure inhalation of anthrax to prevent disease progression and for prophylaxis
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